CAREERS
We are building an experienced and diverse team, where individuality is celebrated, good working culture is prioritised, and team members can learn and progress. We are seeking to grow our team by finding people who share our vision and want to help us bring discoveries to life.
We’re part of the School of Biological Sciences and the School of Clinical Medicine at the University of Cambridge, located on the Cambridge Biomedical Campus. Our Institute provides a unique working environment, with start-up businesses, academics and pharma companies working side by side across office and laboratory space.
Our current vacancies are listed below. If you have questions about any of our roles, or want to know more about our working culture, we would love to hear from you. Email hr@milner.cam.ac.uk.
Join the Frame Shift Teams
Lead Bioinformatician - Cancer Biology, Cosyne Therapeutics
CoSyne Therapeutics is a computational drug discovery company that uses genetic and computational systems to develop next-generation medicines. The company’s first goal is to create a new class of drugs to treat the deadliest form of human brain cancer: Glioblastoma Multiforme. Our novel platform allows us to identify vulnerabilities in cells that no other company or academic institution has done before. We are a highly multidisciplinary team of bioinformaticians, AI specialists, cell biologists and clinicians united around our passion for treating patients with unmet clinical needs.
CoSyne recently closed a substantial seed funding round from industry-leading investors and the company is looking to grow the bioinformatics team. The Lead Bioinformatician (Cancer Biology) will be a key member of the computational team and will enhance the capabilities of the CoSyne computational discovery platform. You will be working in a team of data scientists, machine learning scientists and bioinformaticians. Working closely with the Lead Bioinformatician (Pipelines) and CSO, you will generate biological insights and algorithms to identify novel therapeutic targets.
You will collaborate with a team of wet lab scientists and clinicians around a common goal of helping patients with devastating diseases. You will have the opportunity to access a diverse array of proprietary genomic and functional data at the bleeding edge of science, collaborate with experts from diverse domains, and gain experience using novel computational tools. We are looking for candidates who are excited to tackle some of the greatest challenges in science with us.
Key responsibilities:
• Use computational biology approaches, data integration, and biological knowledge to generate novel therapeutic targets.
• Comprehensively analyse, explore and integrate data from multiple (proprietary and public) sources to build rich biological insights.
• Drive data collection and interpretation by working closely with the machine learning, wet lab and computational biology teams.
• Work with the pipeline team to develop effective and scalable data processing pipelines.
• Build and manage a high-performing and innovative team.
• This role will report to the CSO.
Requirements
• Possess a strong background in bioinformatics / computational biology.
• Demonstrate a deep understanding of cancer biology, WGS/WES, and experience in target discovery.
• Ideally, experience in analysing functional genomic screening (or RNAi) data (e.g. DepMap) and single-cell sequencing.
• 3-4 years’ experience post-PhD (or equivalent time), preferably within biotech or a related industry, with a strong track record of success in leading target ID programs.
• Strong experience analysing genomic data, including data QC, processing and interpretation.
• Demonstrate expertise in one or more of: Python, R, bash/Unix scripting.
• Familiarity with version control software, such as GitHub or GitLab.
• Possess a strong desire to work in a diverse, collaborative and fast-paced environment and a willingness to be hands-on.
• Be kind.
Benefits
• As an early employee of the company, you will be involved in every aspect of the business and help set the direction/culture as we grow.
• The opportunity to work with incredible data and develop cutting-edge computational tools.
• We are building a highly multidisciplinary team and are focused on breaking down silos between the lab and computational biology.
• Membership to CoSyne’s Equity scheme.
• All the perks of a start-up – highly competitive salaries, great IT, team dinners/socials, flexible working, flat structure, and a dynamic work environment.
We interview on a rolling basis and so this role will be filled when we find the right candidate
For more information and to apply for this position please click here
Office Manager (Part-Time or Full-Time), Cosyne Therapeutics
CoSyne Therapeutics is a computational drug discovery company that uses genetic and computational systems to develop next-generation medicines. The company’s first goal is to create a new class of drugs to treat the deadliest form of human brain cancer: Glioblastoma Multiforme. We are a highly multidisciplinary team of bioinformaticians, AI specialists, cell biologists and clinicians united around our passion for treating patients with unmet clinical needs.
recently closed a substantial seed funding round from industry-leading investors and the company is looking to grow the operations team. The Office Manager is a key member of the team and will work across the business to help scale our operations and our great working environment as we scale. Reporting to the VP of Operations, you will work across the company and team. CoSyne is a fast-growing but still small company, and the Office Manager will have to wear many hats to support the day-to-day operations. This role is not solely about office manager duties; we are looking for an individual to help glue our teams together and ensure that we maintain our company culture as we grow.
You will be able to define your role and be given the freedom and responsibility to help streamline and ensure that CoSyne can grow quickly. Due to the cross-functional nature of the work, you will also be critical in creating/maintaining an engaging, fun, and dynamic work environment.
- Act as a personal assistant for the Senior Leadership team, providing administrative support as required.
- Working with our virtual finance office, manage light bookkeeping and credit control, including invoicing and payment processing.
- Maintain accurate records and files for easy retrieval.
- Working with our VP of Operations and HR consultants to help with HR duties and administrative tasks.
- Organise and schedule meetings, appointments and travel arrangements as required.
- Support the team with ad-hoc administrative duties as required.
- Format information for internal and external communication – memos, emails, presentations, reports.
- Help organise team social events and help create an exceptional company culture.
Requirements
- Proven experience as an Office Manager or Personal Assistant. Ideally, within a start-up or small company environment.
- Excellent organisational and time management skills
- Strong attention to detail and accuracy
- Excellent communication and interpersonal skills
- Strong emotional intelligence and a desire to support our team.
- Highly proficient in IT and Microsoft Office suite.
- A “can do” attitude and a mindset of always looking for solutions.
- Be Kind.
Benefits
- As an early employee of the company, you will be involved in every aspect of the business and help set the direction/culture as we grow.
- The opportunity to work independently but with a fun, young and interesting company.
- An ability to grow your skills and career; we want people to grow as the company grows.
- Membership to equity scheme.
- All the perks of a start-up – highly competitive salaries, great IT, team dinners/socials, flexible working, flat structure, and a dynamic work environment.
We have offices in Soho (WeWork) London and labs in Cambridge (Milner Therapeutics Institute). There will be some expectation to travel to the Cambridge site every few weeks.
We interview on a rolling basis and so this role will be filled when we find the right candidate
For more information and to apply for this position please click here
Director of Target Discovery, Cosyne Therapeutics
CoSyne Therapeutics is a computational drug discovery company that uses genetic and computational systems to develop next-generation medicines. The company’s first goal is to create a new class of drugs to treat the deadliest form of human brain cancer: Glioblastoma Multiforme. Our novel platform allows us to identify vulnerabilities in cells that no other company or academic institution has done before. We are a highly multidisciplinary team of bioinformaticians, AI specialists, cell biologists and clinicians united around our passion for treating patients with unmet clinical needs.
CoSyne recently closed a substantial seed funding round from industry-leading investors and the company is looking to grow the bioinformatics team. The Director of Target Discovery will be a key member of the R&D team and will lead CoSyne’s target discovery effort. You will be working in a team cell biologists, molecular biologists and single-cell specialists. Working closely with the Bioinformatic team, AI team and reporting to the CSO, you will be responsible for CoSyne’s target discovery platform. You will collaborate with a team of wet lab scientists and clinicians around a common goal of helping patients with devastating diseases.
You will have the opportunity to lead an exceptional team of scientists at the cutting edge of target discovery, utilising single-cell genomics, functional genomic screens and 3D organotypic cultures. As a well-funded and high-growth company, you will have the freedom and resources to excel.
Key responsibilities
- Working closely with the CSO to manage and drive CoSyne’s target discovery efforts.
- Create and develop innovative target discovery approaches, especially in the field of functional genomics and single cell technologies.
- Work across the R&D teams and CROs to drive forward drug discovery programs and be the thought leader within the company for target discovery.
- Design and execute experiments and assays to validate the therapeutic potential of identified targets, including in vitro and in vivo studies.
- Serve as a key connection point between bioinformatics and AI team to ensure an integrated target discovery approach.
- Lead and build out a team of target discovery scientists, maintaining and further improving a dynamic and faced paced work culture.
- Lead the R&D site in Cambridge and work with the VP of operations to ensure correct functioning of the site.
- Contribute to the development and protection of intellectual property related to novel methods, targets and therapeutic approaches, including patent filing and management.
- Collaborate with other areas within the company, such as business development as well as providing scientific expertise and support in evaluating potential partnerships and licencing opportunities
Requirements
- At least 5 years in Biotech/Pharma background, leading in target discovery efforts. Ideally within a startup environment.
- Ability to develop and execute strategic plans and initiatives in target discovery, solve problems to drive decision-making and target prioritisation
- Demonstrate a deep understanding of experience in a range of target discovery techniques and validation, ideally with the use of genomics. Passion for emerging technologies and trends in target identification and validation is also valued.
- Prior experience in leveraging genomics/proteomics techniques or employing large-scale data analysis approaches to target discovery.
- Deep domain expertise in cell biology and cell manipulation technologies (CRISPR etc)
- Ideally, experience in analysing functional genomic screening (or RNAi) and single-cell sequencing data.
- A background in leading teams and creating high-performing (and fun!) work cultures.
- Possess a strong desire to work in a diverse, collaborative and fast-paced environment and a willingness to be hands-on.
- Be kind.
This role would a principal scientist who is line managing a small team and who wants to make the next step in their career or a Director who is excited to join a fast-growing company
Benefits
What We Offer
- As an early employee of the company, you will be involved in every aspect of the business and help set the direction/culture as we grow.
- The opportunity to work with an incredible team and develop cutting-edge target discovery tools.
- We are building a highly multidisciplinary team and are focused on breaking down silos between the lab and computational biology.
- Membership to CoSyne’s Equity scheme.
- All the perks of a start-up – highly competitive salaries, great IT, team dinners/socials, flexible working, flat structure, and a dynamic work environment.
Our mission is to develop cutting-edge therapeutics that improve the lives of patients.
We interview on a rolling basis and so this role will be filled when we find the right candidate
For more information and to apply for this position please click here
