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X-WR-CALNAME:FGSL webinar – Mini guts in CRISPR screens: Developing an
 d scaling arrayed CRISPR screens in patient-derived organoids
X-WR-CALDESC:The Milner Therapeutics Institute
X-WR-TIMEZONE:Europe/London
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DTSTART:20261025T010000
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SUMMARY:FGSL webinar – Mini guts in CRISPR screens: Developing and sca
 ling arrayed CRISPR screens in patient-derived organoids
DESCRIPTION:FGSL webinar – Mini guts in CRISPR screens: Developing and
  scaling arrayed CRISPR screens in patient-derived organoids\n\nJoin the
  Functional Genomics Screening Laboratory (FGSL) for a webinar with Dr A
 ntigoni Gogolou and Dr Thomas Dennison.\n\n3 December 2026 | 2–3 pm | 
 Online\n\nPatient-derived intestinal organoids retain key genetic and ep
 igenetic features of the donor’s intestinal epithelium\, making them v
 aluable models for studying inflammatory bowel disease and identifying p
 otential therapeutic targets.\n\nAntigoni and Thomas will present a scal
 able workflow for arrayed CRISPR screening in these models\, combining g
 ene editing with high-content imaging. They will share findings from a p
 roof-of-concept screen of 140 genes in organoids from two donors\, revea
 ling both shared and donor-specific targets that reflect patient heterog
 eneity.\n\nThis collaborative project brings together the FGSL\, Bello a
 nd Zilbauer laboratories\, and AstraZeneca. The presentation will be fol
 lowed by Q&amp\;A.\n\nView the abstract and register
URL;VALUE=URI:https://www.milner.cam.ac.uk/events/fgsl-webinar-mini-guts
 -in-crispr-screens-developing-and-scaling-arrayed-crispr-screens-in-pati
 ent-derived-organoids/
UID:urn:uuid:b9937461-9f76-4d5d-815e-e124db555de7
STATUS:CONFIRMED
ORGANIZER:
DTSTAMP:20261107T191207Z
DTSTART;TZID=Europe/London:20261203T140000
DTEND;TZID=Europe/London:20261203T150000
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